ConSIRT on-going projects

Effect of EMLA® patches for reducing pain associated with sterile water injections - a randomized controlled trial

The aim is to study the effect of local anaesthesia (EMLA®) on pain associated with sterile water injections. Healthy volunteers (n=120) will be randomised to one of four groups 1) sterile water injections after application of EMLA patches, 2) isotonic saline injections after application of EMLA patches, 3) sterile water injections after application of placebo patches, 2) isotonic saline injections after application of placebo patches. The study protocol is registered in Clinical Trials.gov (NCT02213185). Data collection started in Sweden in September 2014.

A comparison of two versus four sterile water injections for the relief of back pain in labour: A randomised controlled equivalence trial

In this RCT 354 women will be randomised to two or four injections of sterile water as pain relief for labour pain. The study protocol is registered on the Australian New Zealand Clinical Trials Registry (No ACTRN12613000863730). Data collection started in Australia in December 2014

Impact on Caesarean section rates following injections of sterile water (ICARIS): a multicentre randomised controlled trial

The objective is to determine if sterile water injections, as an intervention for back pain in labour, will reduce the intrapartum caesarean section rate.  In this double-blind RCT  1 866 women will be randomised to either sterile water injections or isotonic saline (placebo). The study protocol is registered on the Australian New Zealand Clinical Trials Registry (No ACTRN12611000221954). Data collection started in Australia in March 2013. One design article is published: http://www.ncbi.nlm.nih.gov/pubmed/23642147

http://brochures.mater.org.au/Home/Brochures/Mater-Mothers-Hospital/Research-project-The-ICARIS-Trial