School of Bioscience
I am a researcher within the Systems Biology Research Centre and focus on Infection biology and Sepsis. Sepsis is serious medical condition characterized by a whole-body inflammatory state, termed systemic inflammatory response syndrome (SIRS), and the presence of an infection. Despite of the development in diagnostic and therapeutic techniques, sepsis remains one of the leading causes of morbidity and mortality worldwide. Early recognition and treatment of sepsis is crucial to improve outcomes and reduce sepsis-related mortality. Ongoing research projects are 1) Development of sepsis diagnosis system 2) Biomarkers in clinical diagnosis and 3) SMARTDIAGNOS - rapid detection of sepsis.
Diagnostic accuracy of procalcitonin, neutrophil-lymphocyte count ratio, C-reactive protein, and lactate in patients with suspected bacterial sepsisLjungström Lars, Pernestig Anna-Karin, Jacobsson Gunnar et al.PLoS ONE, 2017, 12(7).
Evaluation of the QuickFISH and the Sepsityper assays for early identification of etiological agents in bloodstream infection in a clinical routine setting
Retz Karolina, Andersson Sofie, Andersson Carl et al.27th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Vienna, Austria, 22 – 25 April 2017. 2017.
The diagnostic value of PCT as biomarker in patients suspected with community-onset bacterial sepsis
Ljungström Lars, Jacobsson Gunnar, Pernestig Anna-Karin et al.European Congress of Clinical Microbiology and Infectious Diseases. ECCMID, 2017.
Towards a Clinical Support System for the Early Diagnosis of Sepsis
Helldin Tove, Pernestig Anna-Karin, Tilevik DianaDigital Human Modeling - Applications in Health, Safety, Ergonomics, and Risk Management: Health and Safety: 8th International Conference, DHM 2017 Held as Part of HCI International 2017 Vancouver, BC, Canada, July 9–14, 2017, Proceedings, Part II (23-35). Springer, 2017.
Clinical evaluation of commercial nucleic acid amplification tests in patients with suspected sepsisLjungström Lars, Enroth Helena, Claesson Berndt E. B. et al.BMC Infectious Diseases, 2015, 15(1).
Multimarker approach for sepsis diagnostics
Karlsson Diana, Pernestig Anna-Karin, Ljungström Lars25th European Congress of Clinical Mircobiology and Infectious Diseases, Copenhagen, April 25-28, 2015. European Society of ClinicalMicrobiology and Infectious Diseases (ESCMID), 2015.
Neutrophil to lymphocyte count ratio performs better than procalcitonin as a biomarker for bacteremia and severe sepsis in the emergency department
Ljungström Lars, Karlsson Diana, Pernestig Anna-Karin et al.Critical Care, 2015, 19(Suppl 1).
Quicker identification of Gram-positive cocci in clusters in patients with suspected sepsisRetz Carolina, Andersson Sofie, Enroth Helena et al.24th European Congress of Clinical Microbiology and Infectious Diseases, Barcelona (ECCMID), Spain, 10-13 May 2014. 2014.
Evaluation of microarray-based assay for identification of bloodstream bacteria in patients with suspected sepsisOwemyr Ida, Enroth Helena, Ljungström Lars et al.23rd European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Berlin, Germany, 27–30 April 2013. 2013.
Toward Quantifying the Thymic Dysfunctional State in Mouse Models of Inflammatory Bowel Disease
Jansson Andreas, Pernestig Anna-Karin, Nilsson Patric et al.Inflammatory Bowel Diseases, 2013, 19(4), 881-888.