Anna-Karin Pernestig

Research area
I am a researcher within the Systems Biology Research Centre and focus on Infection biology and Sepsis. Sepsis is serious medical condition characterized by a whole-body inflammatory state, termed systemic inflammatory response syndrome (SIRS), and the presence of an infection. Despite of the development in diagnostic and therapeutic techniques, sepsis remains one of the leading causes of morbidity and mortality worldwide. Early recognition and treatment of sepsis is crucial to improve outcomes and reduce sepsis-related mortality. Ongoing research projects are 1) Development of sepsis diagnosis system 2) Biomarkers in clinical diagnosis and 3) SMARTDIAGNOS - rapid detection of sepsis.
Have you seen? The videos are in Swedish - https://youtu.be/mqDcEMKfiIU and https://youtu.be/WyJI40M_pYU
Research
2023
BMC Infectious Diseases
2023. Article.
https://doi.org/10.1186/s12879-022-07977-0
2022
Microbial Pathogenesis
2022. Article.
https://doi.org/10.1016/j.micpath.2022.105836
Nätverksträff för Forskningsbibliotekens pedagogiska roll, Göteborg, 24-25 november, 2022
2022. Conference paper, oral presentation with abstract.
2021
Frontiers in Microbiology
2021. Article.
https://doi.org/10.3389/fmicb.2021.640408
2019
Infectious Diseases
2019. Article.
https://doi.org/10.1080/23744235.2018.1554258
14th Annual Workshop in Systems Biology, University of Skövde, Sweden, 21 November 2019
2019. Conference paper, poster.
14th Annual Workshop in Systems Biology, University of Skövde, Sweden, 21 November 2019
2019. Conference paper, poster.
29th European Congress of Clinical Microbiology and Infectious Diseases, ECCMID, Amsterdam, Netherlands, 13-16 April, 2019
2019. Conference paper, poster.
29th European Congress of Clinical Microbiology and Infectious Diseases, ECCMID, Amsterdam, Netherlands, 13-16 April, 2019
2019. Conference paper, poster.
2018
Laboratory Investigation
2018. Article, review. https://doi.org/10.1038/s41374-018-0143-3
2017
2015
2014
2013
2012
2006
2005
2003
2002
2001
2000
Finished projects
miRSeps - Future diagnostics of sepsis
This project is one of several ongoing projects within the research programme “Future diagnostics for sepsis”. The aim is to develop diagnostics that can be used earlier in cases of sepsis in order to increase the patient’s chances of survival with fewer complications.
January 2020 - June 2023 Systems BiologyData-mining for Biomarker Discovery, Selection, and Validation
In the BioMine project (Data-mining for Biomarker Discovery, Selection, and Validation), studies are performed on how large-scale biomolecular data can be mined to enable discovery and validation of multilevel biomarkers in Life Science.
October 2017 - May 2022 Systems BiologyBiomarkers in clinical diagnosis
This project is one of several ongoing projects in the research "Future diagnostics of sepsis". The goal is to develop earlier and more accurate diagnostics for sepsis in order to increase the chance of patients suffering from survival and with less disease complications.
October 2017 - September 2021 Systems BiologySMARTDIAGNOS – rapid detection of sepsis
This project is one of several ongoing projects in the research "Future diagnostics of sepsis". The goal is to develop earlier and more accurate diagnostics for sepsis in order to increase the chance of patients suffering from survival and with less disease complications.
February 2016 - January 2020 Systems BiologySepsIT® – the development of diagnostic systems for sepsis
This project is one of several ongoing projects within the research programme “Future diagnostics for sepsis”. The aim is to develop diagnostics that can be used earlier in cases of sepsis in order to increase the patient’s chances of survival with fewer complications.
October 2016 - September 2019 Systems BiologyEarly diagnosis of sepsis
This project is one of several ongoing projects in the research "Future diagnostics of sepsis". The goal is to develop earlier and more accurate diagnostics for sepsis in order to increase the chance of patients suffering from survival and with less disease complications.
January 2014 - December 2016 Systems Biology