Finished research projects: Translational Bioinformatics

2015-2018 The pharmaceutical industry has an urgent need for in vitro model systems with high human relevance that can be used for toxicity testing, drug development, and disease modelling. The project aims at developing a human in vitro model based on human pluripotent stem cells that can mimic important aspects of the blood-brain-barrier.

2015-2019 The aim of this project is to contribute with improved methods for analysis, integration, and visualization of biomedical big data. Recent years it has been a massive digitalization of all types of data and information in the society and the majority of all information in the world is nowadays anticipated to be digitalized. This encompasses enormous possibilities for generation of new knowledge but also puts demands on competence and tools for analysis and interpretation of big and complex data, e.g. to identify and extract patterns and information from different data sources. To meet these increasing demands of large-scale data analysis more competence, better and faster algorithms, and powerful computers are needed for execution these algorithms.

2013-2016 Human pluripotent stem cells (hPSC) are characterized by their unique capacities of self-renewal and differentiation, and, as such, they provide an excellent human cell source in basic research, drug discovery and regenerative medicine.