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      Högskolan i Skövde, länk till startsida

      Jane Synnergren

      Bitr. professor bioinformatik
      Institutionen för biovetenskap
      Rum G2262

      I am Associate Professor in bioinformatics at the University of Skövde, Sweden, and Head of the Translational Bioinformatics research group  consisting of a group of 19 researchers with a dedicated interest in bioinformatics. I have a background in Data Science and received my MSc in Computer Sciences from the University of Skövde in 2003.  During my graduate studies I developed my expertise in bioinformatics and large-scale omics data analysis and received my PhD from the University of Gothenburg in 2010.

      My research is focused on analysis methods for identification of biomarkers and integration of multiple types of omics data. I am PI for several research projects specialized in stem cell differentiation, toxicity testing and disease modeling using stem cell based in vitro systems. I am also leading projects particularly focused on advanced analysis of big data, biomarker identification, and data integration with particular interest in machine-learning methods.

      Working in close collaboration with the stem cell industry and the pharmaceutical industry we perform global expression studies including transcriptomics, proteomics, epigenomics, and metabolomics of human pluripotent stem cells during their differentiation towards functional cell types. The results from these studies have revealed mechanistic highlights during the early phases of stem cell differentiation and identified biomarkers with potential importance for applications in toxicity testing, drug development, and disease modeling.

      https://www.researchgate.net/profile/Jane_Synnergren

      Forskning

      Publikationer

      2020

      Nidal Ghosheh, Barbara Küppers-Munther, Annika Asplund, Christian X. Andersson, Petter Björquist, Tommy B. Andersson, Helena Carén, Stina Simonsson, Peter Sartipy, Jane Synnergren

      ACS Omega

      2020. Artikel. https://doi.org/10.1021/acsomega.9b03514 Open Access

      Gustav Holmgren, Benjamin Ulfenborg, Annika Asplund, Karin Toet, Christian X. Andersson, Ann Hammarstedt, Roeland Hanemaaijer, Barbara Küppers-Munther, Jane Synnergren

      International Journal of Molecular Sciences

      2020. Artikel. https://doi.org/10.3390/ijms21020469 Open Access

      Jane Synnergren, Kristina Vukusic, Pierre Dönnes, Marianne Jonsson, Anders Lindahl, Göran Dellgren, Anders Jeppsson, Julia Asp

      Physiological Genomics

      2020. Artikel. https://doi.org/10.1152/physiolgenomics.00036.2019

      2019

      Louise Delsing, Therese Kallur, Henrik Zetterberg, Ryan Hicks, Jane Synnergren

      Fluids and Barriers of the CNS

      2019. Artikel. https://doi.org/10.1186/s12987-019-0147-4 Open Access

      2018

      Louise Delsing, Pierre Dönnes, José Sánchez, Maryam Clausen, Dmitrios Voulgaris, Anna Falk, Anna Herland, Gabriella Brolén, Henrik Zetterberg, Ryan Hicks, Jane Synnergren

      Stem Cells

      2018. Artikel. https://doi.org/10.1002/stem.2908 Open Access

      Gustav Holmgren, Peter Sartipy, Christian X. Andersson, Anders Lindahl, Jane Synnergren

      Toxicological Sciences

      2018. Artikel. https://doi.org/10.1093/toxsci/kfy012

      Barbara Küppers-Munther, A. Asplund, Benjamin Ulfenborg, Jane Synnergren, A. Abadie

      Human Gene Therapy

      2018. Artikel, meeting abstract. https://doi.org/10.1089/hum.2018.29077.abstracts

      Anders Lundin, Louise Delsing, Maryam Clausen, Piero Ricchiuto, José Sanchez, Alan Sabirsh, Mei Ding, Jane Synnergren, Henrik Zetterberg, Gabriella Brolén, Ryan Hicks, Anna Herland, Anna Falk

      Stem Cell Reports

      2018. Artikel. https://doi.org/10.1016/j.stemcr.2018.01.021 Open Access

      Jane Synnergren, Pierre Dönnes

      Open Access journal of Toxicology

      2018. Artikel, forskningsöversikt. https://doi.org/10.19080/OAJT.2018.02.555597 Open Access

      Publicerad: 2020-01-09
      Senast ändrad: 2020-01-09
      Sidansvarig: webmaster@his.se